2023
Clinical Biochemistry
Name: Clinical Biochemistry
Code: QUI13659M
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biochemistry
Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Sustainable Development Goals
Learning Goals
The aim of this Unity is to provide the students with the necessary knowledge to understand the contribution of Clinical Biochemistry for the study of mechanisms of diseases and recognize the Clinical Biochemistry as a valuable tool in diagnosis and treatment monitoring, in disease screening and diagnosis or in the prognosis.
This curricular course should develop instrumental, interpersonal and systemic competences, including competences for research, selected and interpreting scientific contents in Clinical Biochemistry in order to identify, quantify and interpreting the main metabolic markers in metabolic disorders, which allow the students to talk and write on coherent and logical way about these ideas and scientific knowledge in Clinical Biochemistry.
This curricular course should develop instrumental, interpersonal and systemic competences, including competences for research, selected and interpreting scientific contents in Clinical Biochemistry in order to identify, quantify and interpreting the main metabolic markers in metabolic disorders, which allow the students to talk and write on coherent and logical way about these ideas and scientific knowledge in Clinical Biochemistry.
Contents
Basic concepts in Clinical Biochemistry. The problematic of a Clinical Biochemistry Lab. Biological specimens. Collection and handling of biological samples. Quality control. Techniques and methods of analysis used individually or in automatic analysers. Reference values and their clinical significance.
Physiology and pathophysiology of several organs and systems. Biochemical markers. Plasmatic proteins. Nutritional markers. Liver, function and main disorders. Serum enzymes markers on hepatic disease, acute myocardial infarction, pancreatic and muscular disease. Plasmatic lipoproteins, metabolic disorders and risk of cardiovascular disease. Carbohydrate metabolism and glucose homeostasis. Diabetes mellitus. Hypoglycemia and inborn errors of carbohydrate metabolism. Renal function and electrolytes balance. Endocrine function and hormonal disorders. Tumoral markers. Data analysis in Clinical Biochemistry. Interpretation of case studies.
Physiology and pathophysiology of several organs and systems. Biochemical markers. Plasmatic proteins. Nutritional markers. Liver, function and main disorders. Serum enzymes markers on hepatic disease, acute myocardial infarction, pancreatic and muscular disease. Plasmatic lipoproteins, metabolic disorders and risk of cardiovascular disease. Carbohydrate metabolism and glucose homeostasis. Diabetes mellitus. Hypoglycemia and inborn errors of carbohydrate metabolism. Renal function and electrolytes balance. Endocrine function and hormonal disorders. Tumoral markers. Data analysis in Clinical Biochemistry. Interpretation of case studies.
Teaching Methods
The teaching-learning process will be based on the individual work and supported by theoretical and practical classes. Lectures will be supported by audiovisual techniques and recommended bibliography. Practical laboratory classes will be articulated with theoretical concepts.
The laboratory practical component is continuously evaluated based on attendance, planning of experimental work and interpretation and discussion of the results obtained. Additionally, students should present a research project based on the main biochemical markers for diagnosis or monitoring a selected pathology. The theoretical component can be assessed by continuous assessment, with 2 written tests, or by final exam
The final grade is calculated based on the laboratory practical classification (30%), research project and its oral presentation (20%) and the classification of the write component (50%).
The laboratory practical component is continuously evaluated based on attendance, planning of experimental work and interpretation and discussion of the results obtained. Additionally, students should present a research project based on the main biochemical markers for diagnosis or monitoring a selected pathology. The theoretical component can be assessed by continuous assessment, with 2 written tests, or by final exam
The final grade is calculated based on the laboratory practical classification (30%), research project and its oral presentation (20%) and the classification of the write component (50%).
Teaching Staff
