2024
Organic Chemistry Applied to Pharmaceutical Sciences
Name: Organic Chemistry Applied to Pharmaceutical Sciences
Code: QUI13728I
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Chemistry
Teaching languages: Portuguese, English
Languages of tutoring support: Portuguese
Regime de Frequência: Presencial
Presentation
The UC presents several aspects about the structure, physical-chemical properties, and methods of synthesis and characterization of the most representative functional groups in Organic Chemistry, important in the area of Pharmaceutical Sciences.
Sustainable Development Goals
Learning Goals
In this curricular unit, it is intended that students:
- acquire fundamental knowledge about the structure, physical-chemical properties and methods of synthesis of the most representative functional groups in Organic Chemistry;
- understand the structural aspects that influence the reactivity of organic compounds and be able to predict their chemical behavior;
- describe and interpret the reactivity of organic molecules and the mechanism of these reactions;
- know the fundamentals of the spectroscopic methods of 1H and 13C nuclear magnetic resonance, infrared and ultraviolet-visible, and mass spectrometry, and use these methods to interpret the spectra and to do the structural elucidation of organic compounds.
It is also intended that students continue to progress their ability and safety at the laboratory, to develop the design and execution skills of the laboratory work, as well as the critical sense and the capabilities to solve problems.
- acquire fundamental knowledge about the structure, physical-chemical properties and methods of synthesis of the most representative functional groups in Organic Chemistry;
- understand the structural aspects that influence the reactivity of organic compounds and be able to predict their chemical behavior;
- describe and interpret the reactivity of organic molecules and the mechanism of these reactions;
- know the fundamentals of the spectroscopic methods of 1H and 13C nuclear magnetic resonance, infrared and ultraviolet-visible, and mass spectrometry, and use these methods to interpret the spectra and to do the structural elucidation of organic compounds.
It is also intended that students continue to progress their ability and safety at the laboratory, to develop the design and execution skills of the laboratory work, as well as the critical sense and the capabilities to solve problems.
Contents
1. Spectroscopic and spectrometric methods applied to the structural elucidation of organic molecules: proton and carbon-13 nuclear magnetic resonance, infrared and ultraviolet-visible spectroscopies, and mass spectrometry.
2. Study of the structure, physical-chemical and spectral properties, synthetic methodologies and reactivity of organic compounds with the following functional groups:
- alcohols,
- phenols,
- ethers,
- thiols,
- alkyl halides,
- amines,
- aldehydes,
- ketones,
- carboxylic acids,
- carboxylic acids derivatives: acid halides, carboxylic anhydrides, esters, amides and nitriles.
3. Aliphatic and aromatic heterocycles: nomenclature, structure, properties, synthetic methodologies, and reactivity.
2. Study of the structure, physical-chemical and spectral properties, synthetic methodologies and reactivity of organic compounds with the following functional groups:
- alcohols,
- phenols,
- ethers,
- thiols,
- alkyl halides,
- amines,
- aldehydes,
- ketones,
- carboxylic acids,
- carboxylic acids derivatives: acid halides, carboxylic anhydrides, esters, amides and nitriles.
3. Aliphatic and aromatic heterocycles: nomenclature, structure, properties, synthetic methodologies, and reactivity.
Teaching Methods
The teaching / learning process is based on the individual work of the students, supported by the bibliography recommended by the teacher. Theoretical classes are exposition classes, taking place to clarify doubts and discuss relevant topics. Theoretical-practical classes allow the deepening of knowledge through the resolution of exercises.
The laboratory classes use the planning and execution of experimental work that apply practical examples of the contents taught.
The assessment is based on measuring the acquisition and understanding of knowledge and the development of skills by the student. The evaluation of the theoretical and theoretical-practical component is carried out by the average of two tests or by a final exam (75%). The evaluation of the practical component is obtained based on participation in classes, the execution of practical assignments and the preparation of reports by the student (25%).
The laboratory classes use the planning and execution of experimental work that apply practical examples of the contents taught.
The assessment is based on measuring the acquisition and understanding of knowledge and the development of skills by the student. The evaluation of the theoretical and theoretical-practical component is carried out by the average of two tests or by a final exam (75%). The evaluation of the practical component is obtained based on participation in classes, the execution of practical assignments and the preparation of reports by the student (25%).
Teaching Staff
- António Paulo da Silva Teixeira [responsible]
Certificações
