2024

Pharmaceutical Microbiology I

Name: Pharmaceutical Microbiology I
Code: CMS13738I
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area: Biochemistry, Biological Sciences

Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial

Presentation

Pharmaceutical Microbiology aims to provide students with a set of knowledge that allows them to know the fundamentals of Microbiology in the field of life sciences and recognize the role of microorganisms as agents of changes in pharmaceutical products.

Sustainable Development Goals

Learning Goals

The general objective of this curricular unit is to provide students with a set of knowledge that allows them to know the fundamentals of Microbiology, recognizing the biochemical, morphological and genetic differences of microorganisms and the aspects related to the control of microbial growth. It is also intended that students recognize the relevance of Microbiology in the field of life sciences and recognize the role of microorganisms as agents of changes in pharmaceutical products. It is also intended that students acquire skills to perform laboratory procedures used in the study of microorganisms and to follow safety standards in Microbiology.

Contents

Microbiology: importance and its historical context.
Taxonomic position of microorganisms in all living beings. Main groups of microorganisms. Main cellular structures and function.
Principles of microbial metabolism. Cellular transport of nutrients. Nutritional requirements. Energetic and biosynthetic metabolism. Metabolic strategies. Breathing and fermentation. Cell growth physiology.
Microbial diversity. Classical and molecular classification methods. Phylogenetic classification.
Bacteria, fungi and viruses of industrial, environmental and public health interest.
Antimicrobial control. Distinction between microbiostatic, microbicidal and microbiolitic effects. Sterilization, disinfection, antisepsis concepts. Physical and chemical methods of antimicrobial control.
Microorganisms as agents of alterations of pharmaceutical products in Pharmaceutical biotechnology in the production of drugs, therapeutic proteins and vaccines.


Teaching Methods

The teaching is based on theoretical, practical and tutorials classes. The laboratory classes are coordinated and complementary to the theoretical, applying the subjects in concrete practical situations. The tutorial guidelines will serve to support scientific-pedagogical monitoring of students, particularly in implementing a complementary and integrator work.

The evaluation process will be based on the individual work and on the progress in the theoretical and practical components of this curricular unit.
Practical component will be continuously evaluated by the student assiduity, previous preparation and planning of experimental work and laboratorial work team performance.
The individual final evaluation will be calculated by: a) Realization of 2 tests or an exam (60%); b) Practical evaluation (40%).