Pharmacotherapeutics and Pharmacoresistance

Code: QUI14090I

3 ECTS

Duration: 15 weeks/78 hours

Scientific Area: Veterinary Medicine

Teaching languages: Portuguese

Languages of tutoring support: Portuguese, English

Regime de Frequência: Presencial

Presentation

Sustainable Development Goals

Saúde e bem-estar - Assegurar uma vida saudável e promover o bem-estar para todos, em todas as idades.

Educação de qualidade - Assegurar a educação inclusiva, e equitativa e de qualidade, e promover oportunidades de aprendizagem ao longo da vida para todos.

Trabalho decente e crescimento económico - Promover o crescimento económico sustentado, inclusivo e sustentável, emprego pleno e produtivo, e trabalho decente para todos.

Learning Goals

This course aims to provide the students with:
- The knowledge to support the appropriate use of medication in different clinical conditions, considering, evaluating and managing their potential risks for animal and public health.
- The skills to choose, interpret, discuss, evaluate, and use the appropriate therapeutic approach, mastering the application and administration of the different medication.
- Identify health risks associated with pharmacoresistance (human and animal) and emerging pharmacoresistances in veterinary medicine
- Investigate potential treatment solutions, highlighting the repurposing phenomenon and/or new molecules being tested
- Know how to act (prophylactic and therapeutic technique) according to the monitoring and control plans implemented (national and international strategies).

Vegetative nervous system drugs with mimetic and lytic action on the cholinergic, adrenergic and dopaminergic systems. Neuromuscular transmission drugs; Autoacoids. Cardiovascular drugs. Blood pharmaceuticals. Urinary, respiratory and genital tract drugs. Drugs of the digestive tract of monogastric and polygastric animals. Topical organotropic drugs. Anti-inflammatory steroids and non-steroids drugs. Antineoplastic chemotherapy and immunopharmacology. Techniques and methods for individual and/or group prescription. Pharmacological therapy in Veterinary Medicine. Raising awareness of the Pharmacovigilance importance. Pharmacoresistance: definition and scope. Drug resistance in public health - economic and socio-environmental implications. Drugs with proven resistance and / or with potential loss of function. Pharmacoresistance mechanisms: genetic and molecular bases. Pharmacoresistance mitigation strategies. Drug monitoring and control programs.

Teaching Methods

Theoretical sessions for the transmission of fundamental knowledge where active methodologies that appeal to student/student interaction will be used, such as debates, group/peer research work, problem-solving, and exploration of case studies, favoring cooperative learning. Theoretical teaching and information sharing sessions combine evidence of drug resistance with interactive case-study debate (TP classes) where clinical reasoning and an appropriate therapeutic approach are stimulated.
The evaluation will be carried out in three ways: one, in a group, by the presentation and discussion of results obtained from the realization of problems (30%); another for the oral presentation of a case study related to the subject taught (25%); the third by written evaluation (45%) in a total = 25% + 35% + 45%. It can also be through 2 written tests in the middle (50%) and at the end of the semester (50%) or just one final written exam (100%).