2023
Clinical Immunology
Name: Clinical Immunology
Code: CMS14319L
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Health Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Presentation
Study of human immunology, namely the diagnosis, pathogenesis, prognosis and treatment of human diseases.
Sustainable Development Goals
Learning Goals
Integrate knowledge of the basic mechanisms of immune responses and their role in maintaining health and in the genesis of human pathologies. Know the principles of clinical and laboratory diagnosis of diseases in the field of immunopathology. Know the principles of immunological-based therapeutic modulation.
At the end of the Curricular Unit, students must acquire the following skills and competences:
A. Demonstrate knowledge about situations of immune dysfunction in medical practice and immunological-based therapies.
B. Use knowledge of basic immunology in the interpretation of health maintenance and human pathologies.
C. Describe the main situations of immunopathology and the methods for collecting and interpreting clinical and laboratory information to formulate a diagnosis and monitor the evolution of the pathology.
D. Demonstrate ability to effectively communicate technical and scientific data.
E. Demonstrate ability for continuous personal development
At the end of the Curricular Unit, students must acquire the following skills and competences:
A. Demonstrate knowledge about situations of immune dysfunction in medical practice and immunological-based therapies.
B. Use knowledge of basic immunology in the interpretation of health maintenance and human pathologies.
C. Describe the main situations of immunopathology and the methods for collecting and interpreting clinical and laboratory information to formulate a diagnosis and monitor the evolution of the pathology.
D. Demonstrate ability to effectively communicate technical and scientific data.
E. Demonstrate ability for continuous personal development
Contents
1. The Immune System and its components
2. Immune responses and effector mechanisms
3. The Immune System in Health and Disease
4. Hypersensitivity reactions (type I to IV). Clinical and immunopathological aspects of the most frequent pathologies.
5. Infection and immunopathology
6. Primary and secondary immunodeficiencies. HIV infection.
7. Autoimmune diseases: Immunopathology and study methods. Specific and non-specific organ situations.
8. Exercise and the inflammatory/immunological response
9. Transplantation: Rejection of transplants; Xenogenic transplants.
10. Immunomodulation (vaccination): passive and active immunization, prophylactic and therapeutic.
11. Monoclonal antibodies for clinical use.
practical program
A). Immunoglobulin purification
B). Natural immunity test
C). Immunoprecipitation Tests
D). Immunochromatographic tests
E). immunoenzymatic tests
F). Experimental immunization and evaluation of its evolution
2. Immune responses and effector mechanisms
3. The Immune System in Health and Disease
4. Hypersensitivity reactions (type I to IV). Clinical and immunopathological aspects of the most frequent pathologies.
5. Infection and immunopathology
6. Primary and secondary immunodeficiencies. HIV infection.
7. Autoimmune diseases: Immunopathology and study methods. Specific and non-specific organ situations.
8. Exercise and the inflammatory/immunological response
9. Transplantation: Rejection of transplants; Xenogenic transplants.
10. Immunomodulation (vaccination): passive and active immunization, prophylactic and therapeutic.
11. Monoclonal antibodies for clinical use.
practical program
A). Immunoglobulin purification
B). Natural immunity test
C). Immunoprecipitation Tests
D). Immunochromatographic tests
E). immunoenzymatic tests
F). Experimental immunization and evaluation of its evolution
Teaching Methods
1. Theoretical exposition by the teacher
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
Teaching Staff
