2024

Mechanisms and Determination of Structure in Organic Chemistry

Name: Mechanisms and Determination of Structure in Organic Chemistry
Code: QUI13582D
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area: Chemistry

Teaching languages: Portuguese
Languages of tutoring support: Portuguese

Sustainable Development Goals

Learning Goals

The students will be expected to be able to understand the precise ways that molecules react to form other molecules (i.e. the mechanism). They will learn about physical and other methods used to probe the mechanism. These skills will allow the students to plan and devise new reactions that will lead to important final compounds such as drugs, health care projects, energy trapping devices in a sustainable way.
The students will become more experienced in problem solving; principally in the context of chemical reactivity.
The students will learn about new and powerful analytical techniques for the structural determination of organic molecules.

Contents

Provide knowledge on important issues regarding the reactivity of organic compounds, such as advanced pericyclic reactions, mechanisms and their determination, quantitative activity-structure relationships (QSAR) and the stability and reactivity of cyclic compounds.
Provide knowledge on the various spectroscopic and spectrometric techniques for structural analysis of organic compounds.

2D NMR (COSY, HMBC, HMQC, INADEQUATE, NOESY, TOCSY,...).
NMR of other important nuclei (15N, 19F, 31P e 29Si).

Mass spectrometry; analysis of the decomposition profiles of various organic compounds.

Teaching Methods

Throughout the semester different teaching methods are used. In addition to classroom teaching, the student is also motivated to solve various exercises at home. The University's e-learning platform is also used to disseminate the material used in the classes and to conduct mini-tests.
The assessment will be based on measuring the acquisition and understanding of knowledge and measuring the development of skills in the various components of the discipline. The evaluation of the theoretical components will take place through a final exam through a written test (representing 75% of the final grade). This assessment is complemented by the continuous assessment of the students' performance during the semester, by mini-tests (online) and by their participation in seminars (representing 25% of the final grade).