2024
Medical Biotechnology
Name: Medical Biotechnology
Code: CMS14309L
3 ECTS
Duration: 15 weeks/78 hours
Scientific Area:
Biomedical Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Presentation
Study of biotechnology and its applications for intervention in the prophylaxis and therapeutics of human pathologies.
Sustainable Development Goals
Learning Goals
Integrate knowledge of the basic mechanisms for obtaining therapeutic recombinant molecules to be used in various human pathologies. Know the processes and methodologies to be used in the diagnosis and therapeutic interventions in human pathologies.
1. Understand Biotechnology as an integration and application of scientific knowledge, especially in the field of Biological Sciences and Medical Sciences.
2. Familiarization with technologies for creating recombinant organisms to obtain new products and processes. The new biotechnology medicinal products.
3. Describe the clinical use of transgenic animals in diagnosis and testing of new drugs.
4. Understand the concepts and methodologies for intervention in human genetic diseases.
5. The practical and laboratory work will allow the exercise of some techniques directly related to biotechnological applications to be studied in the theoretical component
1. Understand Biotechnology as an integration and application of scientific knowledge, especially in the field of Biological Sciences and Medical Sciences.
2. Familiarization with technologies for creating recombinant organisms to obtain new products and processes. The new biotechnology medicinal products.
3. Describe the clinical use of transgenic animals in diagnosis and testing of new drugs.
4. Understand the concepts and methodologies for intervention in human genetic diseases.
5. The practical and laboratory work will allow the exercise of some techniques directly related to biotechnological applications to be studied in the theoretical component
Contents
Theoretical program
1. Introduction to the concept of applied biotechnology in health areas.
2. Basic principles of gene cloning to obtain products and analysis of therapeutic DNAs and proteins
3. Microbial and eukaryotic cell systems used in Biotechnology
4. Transgenic animals as tools for the study of pathologies and medicines for human use.
5. Applications of gene cloning in the development of new Biotechnology drugs.
6. New advanced therapies for intervention in genetic pathologies: expression control and gene alterations.
Practical program
1. Culture of recombinant bacteria
2. Preparation of plasmid DNA (Miniprep)
3. Restriction enzyme digestion and plasmid DNA analysis
4. Preparation of competent bacteria and transformation
5. Selection of recombinants.
1. Introduction to the concept of applied biotechnology in health areas.
2. Basic principles of gene cloning to obtain products and analysis of therapeutic DNAs and proteins
3. Microbial and eukaryotic cell systems used in Biotechnology
4. Transgenic animals as tools for the study of pathologies and medicines for human use.
5. Applications of gene cloning in the development of new Biotechnology drugs.
6. New advanced therapies for intervention in genetic pathologies: expression control and gene alterations.
Practical program
1. Culture of recombinant bacteria
2. Preparation of plasmid DNA (Miniprep)
3. Restriction enzyme digestion and plasmid DNA analysis
4. Preparation of competent bacteria and transformation
5. Selection of recombinants.
Teaching Methods
1. Theoretical exposition by the teacher
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
