2024

Applied Immunology

Name: Applied Immunology
Code: CMS13734I
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area: Biochemistry, Biological Sciences

Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial

Presentation

This UC aims to sensitize students to the current importance of immunology and to the knowledge of the organs, cells and molecules involved and to understand the maintenance of functional homeostasis and the mechanisms of immune responses.

Sustainable Development Goals

Learning Goals

1. Understanding of the functional homeostasis in animals through the immunological system. Life support.
2. Study of the organs, cells and molecules responsible for the immune responses.
3. Understanding of the immune mechanisms for the discrimination of self and non-self.
4. Laboratory exercises for the study of the immune responses of animals.

Contents

1. Theoretical programme
a. Introduction to the immune system. General aspects.
b. Components of the immune system
c. Antigens and antibodies
d. Gene organisation and expression of immunoglobulin’s
e. Immune responses
f. Effector mechanisms of the immune response
g. The immune system in the health and disease
h. Monoclonal antibodies
i. Experimental immunology

2. Laboratory programme
a. Introduction. Programming of the course
b. Experimental immunisation
c. Purification of immunoglobulin’s
d. Test to the students natural immunity
e. Immunoprecipitation techniques
f. Observation of blood cells
g. ELISA

3. Autonomous laboratory work: chicken immunisation and its characterisation.

Teaching Methods

1. Theoretical presentations

2. Bench working according with:
a. predefined technical protocols
b. Oriented free laboratory work

3. Monograph public presentations

The evaluation of the theoretical component, by continuous assessment of frequencies or final examination, will have a relative weight of 70%.
The practical component will be evaluated by the report of the work performed; it will have a relative weight of 15%.
The evaluation of the monograph and its public presentation will have a relative weight of 15%.
If and when it is possible to do all teaching in the classroom, the relative weight of the monograph and the practical component will be reduced to 10% and 10% will be attributed to the attendance of students to all the components.