2024
Clinical Pharmacology and Toxicology
Name: Clinical Pharmacology and Toxicology
Code: CMS14415L
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biochemistry, Biological Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Presentation
Knowledge of pharmacology and application of pharmacological principles and methods to real situations. Study of effects, explanation of mechanisms of action and degree of risk of toxic's exposure. Promotion and safe and rational use of medicines, management and prevention of exposure to xenobiotcs.
Sustainable Development Goals
Learning Goals
Objectives
Distinguish between action and effect
Understanding the mechanisms of absorption, distribution, metabolism and distribution of xenobíótiocos
Knowing the different modes of action of several drugs
Knowing the factors affecting toxicity
Knowing the different toxic responses to xenobiotics
Competences
Understand the importance of structure and form of the xenobiotic esterioquímica to determine the mechanisms of absorption, distribution, metabolism and distribution
Infer the change of the pharmacological effect of toxic effect
Select and apply knowledge in the formulation of hypotheses, experimental design, and obtaining and processing of results, with a view to problem solving qualitative or quantitative in nature within the family matters dealt.
Distinguish between action and effect
Understanding the mechanisms of absorption, distribution, metabolism and distribution of xenobíótiocos
Knowing the different modes of action of several drugs
Knowing the factors affecting toxicity
Knowing the different toxic responses to xenobiotics
Competences
Understand the importance of structure and form of the xenobiotic esterioquímica to determine the mechanisms of absorption, distribution, metabolism and distribution
Infer the change of the pharmacological effect of toxic effect
Select and apply knowledge in the formulation of hypotheses, experimental design, and obtaining and processing of results, with a view to problem solving qualitative or quantitative in nature within the family matters dealt.
Contents
Xenobiotics with pharmacological and toxicological interest
Pharmacological and toxicological kinetics
Absorption, distribution, metabolism and excretion
Pharmacological and toxicological dynamics
Local action and action at a distance
Shape and structural stereochemistry of xenobiotics
Pharmacology
Different classes of drugs
Drugs that act at neuroefectors junctions and peripheral synapses
Drugs with actions on the central nervous system
Autacoids
Drugs affecting renal and cardiovascular functions
Drugs affecting gastrointestinal function
Chemotherapy anti-microbial and anti-parasitic
Chemotherapy of neoplastic diseases
Immunomodulation therapy
Drugs acting on blood and blood forming organs
Hormones and their antagonists
Toxicology
Factors affecting toxic response, metabolism and disposition
Toxic responses of xenobiotics
Biochemical mechanisms of toxicity
Pharmacological and toxicological kinetics
Absorption, distribution, metabolism and excretion
Pharmacological and toxicological dynamics
Local action and action at a distance
Shape and structural stereochemistry of xenobiotics
Pharmacology
Different classes of drugs
Drugs that act at neuroefectors junctions and peripheral synapses
Drugs with actions on the central nervous system
Autacoids
Drugs affecting renal and cardiovascular functions
Drugs affecting gastrointestinal function
Chemotherapy anti-microbial and anti-parasitic
Chemotherapy of neoplastic diseases
Immunomodulation therapy
Drugs acting on blood and blood forming organs
Hormones and their antagonists
Toxicology
Factors affecting toxic response, metabolism and disposition
Toxic responses of xenobiotics
Biochemical mechanisms of toxicity
Teaching Methods
Collective Sessions Contact transmission of fundamental knowledge which will be used methodologies active calling for the interaction student / student, such as practical activities, discussions, research work in groups / pairs, problem solving / exploration of situations STS & E, which allows learning cooperative, very effective method to solve problems and promote learning. The assessment is done in two ways: one in group, the presentation and discussion of relevant scientific articles. For a better ranking, a written evaluation, by choice, by the completion of two written test in the meddle and at the end of the semester or just a final written exam.
