2025
Applied Analytical Chemistry
Name: Applied Analytical Chemistry
Code: QUI13736I
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Chemistry
Teaching languages: Portuguese, English
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Presentation
The unit Applied Analytical Chemistry aims to provide students with a comprehensive and integrated approach of the theoretical concepts and practical applications of Analytical Chemistry, mainly applied in Pharmaceutical Sciences.
Sustainable Development Goals
Learning Goals
The main objective of this course is to provide students with a set of knowledge in the field of Analytical Chemistry. Specifically, it is intended that students understand the fundamentals of Analytical Chemistry, namely the basic principles of analytical methods and techniques, classic or modern, with greater application in the field of Pharmaceutical Sciences. Thus, students should understand the fundamentals of classical techniques, such as volumetric analysis, but also the principles of advanced methods like the chromatographic and hyphenated techniques, namely Liquid (LC) and Gas (GC) Chromatography coupled with Mass Spectrometry (MS) that in last decades have become fundamental for the analysis of pharmaceutical compounds. Students must also be able to solve problems related to the theoretical concepts and to develop laboratory projects using the various analytical techniques.
Contents
- Introduction to Analytical Chemistry: types of chemical analysis; quantitative and qualitative analysis; sampling and sample preparation; types of error and statistical analysis of the results.
- Introduction to Volumetric Methods: direct, return and indirect titrations; standards; titration end and equivalence point; classification of volumetric methods.
- Volumetric analysis: precipitation, acid-base, complexation and oxidation-reduction; basic concepts review; titration curves derivation; different types of indicators; application examples.
- Introduction to Chromatographic Methods: theoretical basis of chromatography; classification of chromatographic methods; thin layer chromatography (TLC); column chromatography (CC); high performance liquid chromatography (HPLC); gas chromatography (GC); hyphenated techniques, HPLC and GC coupled to mass spectrometry (MS); new developments and examples of application to Pharmaceutical Sciences.
- Introduction to Volumetric Methods: direct, return and indirect titrations; standards; titration end and equivalence point; classification of volumetric methods.
- Volumetric analysis: precipitation, acid-base, complexation and oxidation-reduction; basic concepts review; titration curves derivation; different types of indicators; application examples.
- Introduction to Chromatographic Methods: theoretical basis of chromatography; classification of chromatographic methods; thin layer chromatography (TLC); column chromatography (CC); high performance liquid chromatography (HPLC); gas chromatography (GC); hyphenated techniques, HPLC and GC coupled to mass spectrometry (MS); new developments and examples of application to Pharmaceutical Sciences.
Teaching Methods
Interactive teaching methods will be used to teach the syllabus, in addition to e-learning activities and laboratory work, capable of motivating and promoting the individual learning and the critical participation of students in the classroom sessions.
Assessment
Assessment of the practical laboratory component (NPL):
The assessment of the practical laboratory component is based on the students' practical work reports and their performance in the practical laboratory classes. A mark of 10 or above is required to pass the practical laboratory component.
Assessment of theoretical component (NT):
Students can choose between continuous assessment (frequencies and assignments) or final assessment (exam). In the continuous modality there are two frequencies, one in the middle of the semester (1st Freq) and one at the end (2nd Freq), and one assignment (Trab) throughout the semester. Only students with a mark of 8 or above in the 1st frequency are admitted to the 2nd frequency.
In the examination mode, an examination is taken in the normal and/or appeal season.
Students pass the theoretical part of the subject only if they obtain a final weighted average of the continuous assessment or exam grade equal to or greater than 10:
NT = 40% NTrab + 30% N1ªFreq + 30% N2ªFreq or NT = NE
?
Continuous assessment final grade (NFac):
NFac = 70% NT + 30% NPL
Final grade in the final assessment scheme (NFaf):
NFaf = 70% NT + 30% NPL
The assessment of the practical laboratory component is based on the students' practical work reports and their performance in the practical laboratory classes. A mark of 10 or above is required to pass the practical laboratory component.
Assessment of theoretical component (NT):
Students can choose between continuous assessment (frequencies and assignments) or final assessment (exam). In the continuous modality there are two frequencies, one in the middle of the semester (1st Freq) and one at the end (2nd Freq), and one assignment (Trab) throughout the semester. Only students with a mark of 8 or above in the 1st frequency are admitted to the 2nd frequency.
In the examination mode, an examination is taken in the normal and/or appeal season.
Students pass the theoretical part of the subject only if they obtain a final weighted average of the continuous assessment or exam grade equal to or greater than 10:
NT = 40% NTrab + 30% N1ªFreq + 30% N2ªFreq or NT = NE
?
Continuous assessment final grade (NFac):
NFac = 70% NT + 30% NPL
Final grade in the final assessment scheme (NFaf):
NFaf = 70% NT + 30% NPL
Teaching Staff
Accreditations and Certifications
