2023
Human Microbiome
Name: Human Microbiome
Code: CMS14313L
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biomedical Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Presentation
UC to understand the relationships between the human organism and the microorganisms that inhabit it and between the different microbiomes (intestinal, mucosal, skin) and health disorders; and interpret the dynamics of its evolution as a function of different parameters (age, gender, diet).
Sustainable Development Goals
Learning Goals
Understand the symbiotic relationship between the human organism and the microorganisms that inhabit the human body;
Identify the main microorganisms present in the human body in the absence of disease;
Understand the relationship between the microbiome and health disorders;
Knowing the intestinal, mucosal and skin microorganisms and framing their role in the inflammatory processes of different pathologies
Interpret the dynamics of microbiome evolution as a function of different parameters (age, gender, diet, etc.)
Vertical transmission of microorganisms
Know the methodologies for the study and analysis of the human microbiome
Identify the main microorganisms present in the human body in the absence of disease;
Understand the relationship between the microbiome and health disorders;
Knowing the intestinal, mucosal and skin microorganisms and framing their role in the inflammatory processes of different pathologies
Interpret the dynamics of microbiome evolution as a function of different parameters (age, gender, diet, etc.)
Vertical transmission of microorganisms
Know the methodologies for the study and analysis of the human microbiome
Contents
THEORETICAL COMPONENT
1. Introduction
2. Composition of the human microbiome
3. Dynamics of the Microbiome
4. Role of the microbiome in human homeostasis
5. Modes of transmission of microorganisms between individuals
6. Components of the microbiome
7. Modes of microbiome variation
8. Clinical intervention in the microbiome
9. Microbiome analysis
PRACTICAL COMPONENT
Laboratory application of aseptic techniques and the concept of sterility
Isolation and summary characterization of bacteria and viruses
Brief analysis of the diversity of microorganisms present in the human oral mucosa
THEORETICAL PRACTICAL COMPONENT
Thematic monographs to be prepared and presented by students
1. Introduction
2. Composition of the human microbiome
3. Dynamics of the Microbiome
4. Role of the microbiome in human homeostasis
5. Modes of transmission of microorganisms between individuals
6. Components of the microbiome
7. Modes of microbiome variation
8. Clinical intervention in the microbiome
9. Microbiome analysis
PRACTICAL COMPONENT
Laboratory application of aseptic techniques and the concept of sterility
Isolation and summary characterization of bacteria and viruses
Brief analysis of the diversity of microorganisms present in the human oral mucosa
THEORETICAL PRACTICAL COMPONENT
Thematic monographs to be prepared and presented by students
Teaching Methods
1. Theoretical exposition by the teacher
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
2. Carrying out laboratory work, following the experimental protocol provided
3. Preparation and public presentation of thematic monograph by students (group work).
