2025
Disease: from mechanisms to the clinic II
Name: Disease: from mechanisms to the clinic II
Code: CMS15074M
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biomedical Sciences, Health Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Regime de Frequência: Presencial
Sustainable Development Goals
Learning Goals
This course is structured so that students can acquire knowledge and skills about the structure and function of the 1) Nervous System, 2) Thoracic and Vascular System, 3) Hematopoietic System and 4) Immune System. The aim is also to enable students to discuss clinical cases and stimulate the use of creative and critical skills (critical analysis of the bibliography). The aim is also to develop oral and written communication skills and group work.
At the end of the course, students should be able to understand and describe the molecular mechanisms underlying the pathologies of the systems studied, identify means of diagnosis and know the main therapeutic strategies for each of them.
At the end of the course, students should be able to understand and describe the molecular mechanisms underlying the pathologies of the systems studied, identify means of diagnosis and know the main therapeutic strategies for each of them.
Contents
1.Nervous System diseases
Neuro-muscular diseases (D)D. of the spinal cord. D. of movement. Myelin disorders. Dementias. Cerebral vascular accidents. Tumors of the Central Nervous System.
2.Thoracic and vascular disease
Lung:Lung cancer. Infectious, interstitial and environmental lung pathology. Pleural pathology. Thromboembolism and pulmonary hypertension.
Heart:Coronary artery D. Valvular heart D.Infectious endocarditis. Myocardial Damage, Pericardium and Heart Failure. Brady and tachyarrhythmias. Arterial hypertension. Cardiac tumors. Aneurysms and acute aortic syndromes. Syncope.
Peripheral arterial and venous pathology.
3.Diseases of the Hematopoietic System.
Morphology and function. Red and white blood cell pathology. Alterations in hemostasis. Hemato-Oncological Pathology.
4.Diseases of the Immune System
Hypersensitivities. Autoimmune diseases. Immunodeficiencies. Immunoproliferative syndromes. Neoplasms. Immunoprophylaxis. Immunotherapy (organ transplantation). Immunomodulation
Neuro-muscular diseases (D)D. of the spinal cord. D. of movement. Myelin disorders. Dementias. Cerebral vascular accidents. Tumors of the Central Nervous System.
2.Thoracic and vascular disease
Lung:Lung cancer. Infectious, interstitial and environmental lung pathology. Pleural pathology. Thromboembolism and pulmonary hypertension.
Heart:Coronary artery D. Valvular heart D.Infectious endocarditis. Myocardial Damage, Pericardium and Heart Failure. Brady and tachyarrhythmias. Arterial hypertension. Cardiac tumors. Aneurysms and acute aortic syndromes. Syncope.
Peripheral arterial and venous pathology.
3.Diseases of the Hematopoietic System.
Morphology and function. Red and white blood cell pathology. Alterations in hemostasis. Hemato-Oncological Pathology.
4.Diseases of the Immune System
Hypersensitivities. Autoimmune diseases. Immunodeficiencies. Immunoproliferative syndromes. Neoplasms. Immunoprophylaxis. Immunotherapy (organ transplantation). Immunomodulation
Teaching Methods
The Theoretical classes will be expository, using audiovisual materials made available on Moodle. They will be used mainly to present the fundamental concepts which will then be further developed in the TPs. These will be directed to small groups and will preferably use the flipped classroom (FC) and Problem-Based Learning (PBL) methodology. In the FC, in-depth documents on the topics (previously presented in the Theoretical classes) will be made available in advance on Moodle, for individual preparation, and the will be used to carry out group activities that allow concepts to be applied. TP-PBL classes will allow concepts to be applied to real-life learning scenarios, in particular the discussion of clinical cases. The PL classes are intended for a TBL session that contributes to the construction of knowledge in a collaborative, proactive way, promoting critical thinking and teamwork.
Assessment
The theoretical evaluation is worth 70% and can be done continuously in 2 assessment components, each with 50% weight in the final theoretical grade. Alternatively, a final exam (theoretical and written) can be taken, covering all the contents of the course with a single test.
The theoretical-practical assessment is worth 20% and is carried out through active participation in (10%) and presentation of written work, carried out in groups (10%). The student receives feedback on the initial versions of the work and can improve, with the final product being graded.
The LP assessment is worth 10%.
The final grade (NF) (whether continuous assessment or final assessment) results from the weighting of the T, TP and PL assessment. NF= T*0.7+TP*0.2+PL*0.1.
The theoretical-practical assessment is worth 20% and is carried out through active participation in (10%) and presentation of written work, carried out in groups (10%). The student receives feedback on the initial versions of the work and can improve, with the final product being graded.
The LP assessment is worth 10%.
The final grade (NF) (whether continuous assessment or final assessment) results from the weighting of the T, TP and PL assessment. NF= T*0.7+TP*0.2+PL*0.1.
Certificações
