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2025

Research Methodologies in Biochemistry

Name: Research Methodologies in Biochemistry
Code: QUI13586M
3 ECTS
Duration: 15 weeks/78 hours
Scientific Area: Biochemistry

Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial

Sustainable Development Goals

Learning Goals

Students should acquire knowledge and skills to support experimental design. They should also be provided with the tools for validating analytical methodologies as well as measurements and experimental data. Students should also acquire proficiency in the methods, algorithms and chemometric tools for the purpose of multivariate analysis of experimental data and pattern recognition, for comprehensive applications in Biochemistry. It is also an ultimate goal to instill in the student some habits of reflecting about his scientific work and planning his professional career in scientific research.

Contents

1. Introduction to Chemometrics. Data treatment and information treatment. Chemometrics and related disciplines in other sciences (Econometrics, Biometrics, etc.).

2. Validation of methodologies for Analytical Biochemistry. Validation of experimental results.

3. Experimental planning and optimization.

4. Cluster analysis, principal components and factors.

5. Quantitative structure-activity relationships (QSARs).

6. Planning of a scientific career: local and international scientific systems. Evaluation by peers.

Teaching Methods

- Expositive theoretical lectures, with some interactivity with the students.
- Practical classes, consisting of problem solving assignments with computational practice.

Evaluation methods:
Written exam (100%).

Teaching Staff

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