2025
Biochemical Pharmacology
Name: Biochemical Pharmacology
Code: CMS13554M
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biochemistry
Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Sustainable Development Goals
Learning Goals
Understanding the phenomena that occur from absorption to the metabolism of drugs, distribution and metabolism.
Knowing how the interaction of drugs with sites where they exert their modes of action
Knowing the general principles of action of drugs and the effects caused by them
Distinguish Pharmacokinetics of Pharmacodynamics.
Knowing the different families of drugs and their modes of action and effects.
Knowing how the interaction of drugs with sites where they exert their modes of action
Knowing the general principles of action of drugs and the effects caused by them
Distinguish Pharmacokinetics of Pharmacodynamics.
Knowing the different families of drugs and their modes of action and effects.
Contents
Introduction
Historical Review
Nature as a source of medicines
Part I
Pharmacokinetics
Pharmacodynamics
Pharmacological action and effect
Drug-receptor, ligand-receptor and pharmacodynamic interactions
Increased or decreased effects due to drug action mechanisms
Transduction signals
Effect of drugs
Quantification of the effect of drugs
Quantification of reversible and irreversible effects
Quantitative pharmacodynamic models
Maximum effect and potency of a drug
Effect of agonist and antagonist drugs
Individual variations of drug response
Part II
Drug classes
Drugs that act on synapses and neuroeffective junctions and acting on the central nervous system
Autacoids
Drugs that affect renal and cardiovascular functions and gastrointestinal function
Anti-microbial and anti-parasitic chemotherapy
Chemotherapy of neoplastic diseases
Immunomodulators
Drugs acting on blood and hematopoietic organs
Hormones and their antagonists.
Historical Review
Nature as a source of medicines
Part I
Pharmacokinetics
Pharmacodynamics
Pharmacological action and effect
Drug-receptor, ligand-receptor and pharmacodynamic interactions
Increased or decreased effects due to drug action mechanisms
Transduction signals
Effect of drugs
Quantification of the effect of drugs
Quantification of reversible and irreversible effects
Quantitative pharmacodynamic models
Maximum effect and potency of a drug
Effect of agonist and antagonist drugs
Individual variations of drug response
Part II
Drug classes
Drugs that act on synapses and neuroeffective junctions and acting on the central nervous system
Autacoids
Drugs that affect renal and cardiovascular functions and gastrointestinal function
Anti-microbial and anti-parasitic chemotherapy
Chemotherapy of neoplastic diseases
Immunomodulators
Drugs acting on blood and hematopoietic organs
Hormones and their antagonists.
Teaching Methods
The unit is organized in theoretical and practical group sessions and tutorials.
The collective sessions of theoretical nature are plenary and based on the scientific method, valuing the research of information, the interpretation of results and the development of a critical attitude and scientific rigor.
In practical sessions, the fundamentals of the methods, the experimental procedures and the quantitative problems are solved. In these sessions, students organized by groups should: actively participate in the preparation and execution of the work, in the discussion of the results, and individually prepare the work reports.
The collective sessions of theoretical nature are plenary and based on the scientific method, valuing the research of information, the interpretation of results and the development of a critical attitude and scientific rigor.
In practical sessions, the fundamentals of the methods, the experimental procedures and the quantitative problems are solved. In these sessions, students organized by groups should: actively participate in the preparation and execution of the work, in the discussion of the results, and individually prepare the work reports.
Assessment
The grade may be based on one of the following assessment methods: continuous assessment or final assessment.
Continuous assessment will include:
- Assessment of the practical/laboratory component, which will focus on evaluating knowledge and its application (40%).
- Assessment of the theoretical component will be carried out through two written examinations (60%). The minimum mark required to sit the second assessment must be 8.5 or above, and the average of the two assessments must be 9.5 or above to pass the module.
The final assessment will take the form of a final written examination, for which a mark of 9.5 or above is required to pass the module (100%).
Continuous assessment will include:
- Assessment of the practical/laboratory component, which will focus on evaluating knowledge and its application (40%).
- Assessment of the theoretical component will be carried out through two written examinations (60%). The minimum mark required to sit the second assessment must be 8.5 or above, and the average of the two assessments must be 9.5 or above to pass the module.
The final assessment will take the form of a final written examination, for which a mark of 9.5 or above is required to pass the module (100%).
Teaching Staff
Accreditations and Certifications
