2025
Molecular and Cellular Bases of Exercise
Name: Molecular and Cellular Bases of Exercise
Code: CMS14965L
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biomedical Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese, English
Regime de Frequência: Presencial
Sustainable Development Goals
Learning Goals
The aim of this program course is to provide the students with the basic knowledge necessary to interpret the physiological functions of different cells, tissues and organs essential to human life. In particular, that is possible to answer to some of the hows and whys that emerge from observation and experimentation on physical and sportive activity, through the language of molecular interactions. In this course, students should actively participate in the teaching-learning process, developing the ability to study autonomously, to discuss in groups to solve problems, and to develop oral and written communication skills.
In the end of this course, students will be able to describe the structures and functions of the principal macromolecules, to comprehend cellular energy transformations and main metabolic pathways as well as the underlying regulatory processes, particularly in different physical or sportive activities.
In the end of this course, students will be able to describe the structures and functions of the principal macromolecules, to comprehend cellular energy transformations and main metabolic pathways as well as the underlying regulatory processes, particularly in different physical or sportive activities.
Contents
1. Cell structure, tissues and organs, and the human being as a whole.
2. Water and main inorganic ions in biologic systems.
3. Structural and functional characteristics of biomolecules.
4. Plasma membrane: structure and semi-permeability properties. Diffusions and active transport.
5. From the gene to protein replication, transcription and translation.
6. Enzymes: activities, properties and regulation.
7. Bioenergetics: energy transformation in biochemical reactions and pathways.
8. Levels of regulation of a biochemical pathway.
9. Saccharides, lipid and protein metabolism.
10. Particular regulatory aspects in skeletal, cardiac, hepatic, adipose and brain muscle tissue.
11. integration of metabolism and immediate importance for physical activity, exercise, and health.
2. Water and main inorganic ions in biologic systems.
3. Structural and functional characteristics of biomolecules.
4. Plasma membrane: structure and semi-permeability properties. Diffusions and active transport.
5. From the gene to protein replication, transcription and translation.
6. Enzymes: activities, properties and regulation.
7. Bioenergetics: energy transformation in biochemical reactions and pathways.
8. Levels of regulation of a biochemical pathway.
9. Saccharides, lipid and protein metabolism.
10. Particular regulatory aspects in skeletal, cardiac, hepatic, adipose and brain muscle tissue.
11. integration of metabolism and immediate importance for physical activity, exercise, and health.
Teaching Methods
The TP classes (students ≤25) will use Flipped Classroom (FC) and Problem-based learning (PBL) as preferential methodologies. In FC, resources for individual study will be made available in advance in Moodle, and the face-to-face classes will be used to verify the assimilation and sedimentation of the concepts, carrying out group activities that allow application of these concepts. PBL classes will allow to apply learning scenarios, applying the concepts to a real context, from the perspective of the Sport Science.
The PL (students ≤15), will be in articulation with the TP, promoting knowledge integration and the sedimentation of theoretical concepts through the realization of simple experimental activities. A practical work of evaluation of biochemical marker(s) in a concrete situation of physical exercise is also foreseen.
Both TP and PL classes also aim to allow students to develop methodological skills, data selection and interpretation, and interrelationship and communication.
The PL (students ≤15), will be in articulation with the TP, promoting knowledge integration and the sedimentation of theoretical concepts through the realization of simple experimental activities. A practical work of evaluation of biochemical marker(s) in a concrete situation of physical exercise is also foreseen.
Both TP and PL classes also aim to allow students to develop methodological skills, data selection and interpretation, and interrelationship and communication.
Assessment
The evaluation system is organized to take into account the work done and the achievement obtained in the various components of the discipline (TP and PL). Two evaluation regimes are possible: continuous evaluation (CE) and final evaluation (FE).
PL Evaluation:
Due to its nature, CE regime is preferably, integrating the results of the quantitative evaluation, based on attendance, interest and performance in laboratory classes, preparation of reports and resolution of oral and/or written questions. In case of failure in the CE regime, the LP is evaluated by FE with a laboratory test and a written test. The final PL rating must be ≥ 9.5.
TP Assessment:
The CE regime takes into account all the assessment instruments used in (TPA- 30%), as well as 2 written tests (TPT1 + TPT2: 40%),
In a FE regime, evaluation is based on a final exam.
The final grade of the TP component must be ≥ 9.5.
Final grade (NF):
CE - NF = PL*0.3 + TPA*0.3 +TPT1*0.2 + TPT2*0.2
FE NF = PL*0.3 + TP *0.7
PL Evaluation:
Due to its nature, CE regime is preferably, integrating the results of the quantitative evaluation, based on attendance, interest and performance in laboratory classes, preparation of reports and resolution of oral and/or written questions. In case of failure in the CE regime, the LP is evaluated by FE with a laboratory test and a written test. The final PL rating must be ≥ 9.5.
TP Assessment:
The CE regime takes into account all the assessment instruments used in (TPA- 30%), as well as 2 written tests (TPT1 + TPT2: 40%),
In a FE regime, evaluation is based on a final exam.
The final grade of the TP component must be ≥ 9.5.
Final grade (NF):
CE - NF = PL*0.3 + TPA*0.3 +TPT1*0.2 + TPT2*0.2
FE NF = PL*0.3 + TP *0.7
Teaching Staff
Certificações
