2025

Aspirin:® from chemical principle to its action

Name: Aspirin:® from chemical principle to its action
Code: QUI14835O
3 ECTS
Duration: 15 weeks/78 hours
Scientific Area: Ciências Farmacêuticas, Chemistry

Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Regime de Frequência: B-learning

Sustainable Development Goals

Learning Goals

• Know, adopt, and implement the basic principles of safety practices in laboratories.
• Recognize and substantiate the importance of Aspirin® in clinical therapy.
• Know and understand the chemical basis of synthesizing the active ingredient in Aspirin®.
• Plan the laboratory synthesis, extraction, purification, and analysis of the active ingredient in Aspirin®.
• Synthesize, extract, purify, and analyze the active ingredient of Aspirin® obtained in the laboratory.
• Pharmacologically characterize Aspirin, particularly in terms of pharmacokinetics and pharmacodynamics.
• Relate and integrate the production of the active ingredient of Aspirin® into the 12 Principles of Green
Chemistry and the 2030 Agenda for Sustainable Development.
• Acquire a global vision between the theoretical foundations in Chemistry and Pharmaceutical Sciences, Laboratory Practice, and the Social Impact of Aspirin®.
• Researching and communicating in science: preparing and presenting a poster.

Contents

• Good Laboratory Safety Practices.
• History and Chemistry of Aspirin®.
• Fundamental aspects of the synthesis, purification, and extraction processes.
• Fundamental aspects of the analysis and characterization of organic compounds.
• Pharmacology and Pharmacotherapy of Aspirin: mechanism of action effectiveness, and safety.
• Aspirin® and Sustainability.
• Research and Communication in Science: Fundamental Principles.

Teaching Methods

• At the beginning of each syllabus, the theoretical concepts relating to the syllabus will be taught using an interactive methodology.
• Subsequently, the processes of synthesis, extraction, purification, and analysis of the active
ingredient in Aspirin® will be carried out in the laboratory.
• At all stages, trainees must participate actively and collaboratively in researching, preparing, and
carrying out experimental work, processing and interpreting results, and preparing a group project
(scientific poster).


Assessment

• Assessment is based on the preparation and presentation of one work done in group, scientific poster(50%) and an individual written test (50%) to be taken after the end of the teaching component.
• Assessment presupposes attendance at least 70% of the theoretical and practical components.
• The final assessment will use a quantitative scale of 0-20 points.