2025

Animal Models in Research

Name: Animal Models in Research
Code: MVT12323I
3 ECTS
Duration: 15 weeks/78 hours
Scientific Area: Veterinary Medicine

Teaching languages: Portuguese
Languages of tutoring support: Portuguese

Sustainable Development Goals

Learning Goals

Bioethics applied to the use of animal in research.
Knowledge on ruling and legislation; historical, ethical and socio-cultural frame.
Familiarization of experimental methods and models.
Outline on the suitability of each animal model with respect to the expectations on its applicability.
Knowledge on the bio-safety rules associated with each animal model.
Being able to prepare suitable anaesthetic and analgesic protocols.

Contents

1-Overall perspective of animals and their utility models; The concept of experimental animal.
2-Bioethics applied to the use of animals for experimental purposes:
Biological foundations of bioethics, ethical aspects relating to animal handling used in educational
activities and scientific experimentation, case studies
3-Applicable laws, rules and historical background, ethical and socio-cultural
Selection of standards, maintenance, handling and animal sacrifice model
4. Examples of relevant models:
Use of mice.
Use of small ruminants in the development of biomaterials for orthopaedic and cardiovascular application.
5. Preparation of suitable anaesthetic and analgesic protocols.

Teaching Methods

The classes follow a model of proactive learning methodology, using inverted models in the introduction to the different animal models, the critical analysis of articles with validation of experimental protocols in the light of current legislation and guidelines. The continuous evaluation will be made based on the average of two papers covering legislation, models and experimental protocols (each worth 50%) and approval with 10 values. The final evaluation by exam is by written test.