2024
Clinical Biochemistry
Name: Clinical Biochemistry
Code: QUI13798I
6 ECTS
Duration: 15 weeks/156 hours
Scientific Area:
Biochemistry, Biological Sciences
Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Presentation
Evaluation of the main biochemical biomarkers in health and disease, and understand their contribution in diagnosis, monitoring, prevention and investigation of diseases.
Sustainable Development Goals
Learning Goals
The aim of this Unity is to provide students with a set of knowledge in the field of Clinical Biochemistry in order to understand the biochemical processes in healthy and disease, to apply the diagnostic methods for biochemical markers quantification, to understand the biological and/or analytical factors that can affect the results, as well as recognize the valuable contribute of the biomarkers.
This curricular unit aims to develop a set of interpersonal, instrumental and systematic skills, namely, to describe and interpret the biochemical changes associated with the pathologies, to identify, describe and quantify the main biomarkers, as well as interpreting their contribution in diagnosis, monitoring, prevention and investigation of diseases.
This curricular unit aims to develop a set of interpersonal, instrumental and systematic skills, namely, to describe and interpret the biochemical changes associated with the pathologies, to identify, describe and quantify the main biomarkers, as well as interpreting their contribution in diagnosis, monitoring, prevention and investigation of diseases.
Contents
Basic concepts in Clinical Biochemistry. Collection and handling of biological samples. Automatic analysers in Clinical Lab. Quality control. Reference values and clinical significance.
Biochemical markers. Plasmatic proteins. Serum enzymes markers and laboratorial diagnosis in hepatic diseases, acute myocardial infarction, pancreatic and muscular disease. Plasmatic lipoproteins disorders and risk of cardiovascular disease. Carbohydrate metabolism and glucose homeostasis. Diabetes mellitus. diagnosis and monitoring.
Electrolyte and acid-base balances. Renal function and biomarkers of main disorders. Endocrine disorders. Tumoral markers. Data analysis in Clinical Biochemistry. Interpretation of clinical case studies.
Biochemical markers. Plasmatic proteins. Serum enzymes markers and laboratorial diagnosis in hepatic diseases, acute myocardial infarction, pancreatic and muscular disease. Plasmatic lipoproteins disorders and risk of cardiovascular disease. Carbohydrate metabolism and glucose homeostasis. Diabetes mellitus. diagnosis and monitoring.
Electrolyte and acid-base balances. Renal function and biomarkers of main disorders. Endocrine disorders. Tumoral markers. Data analysis in Clinical Biochemistry. Interpretation of clinical case studies.
Teaching Methods
The teaching-learning process will be based on the individual work and supported by theoretical and practical classes. Lectures will be supported by audiovisual techniques and recommended bibliography. Practical laboratory classes will be articulated with theoretical concepts.
The laboratory practical component is continuously evaluated based on attendance, planning of experimental work and interpretation and discussion of the results obtained. Additionally, students should present a research project based on the main biochemical markers for diagnosis or monitoring a selected pathology. The theoretical component can be assessed by continuous assessment, with 2 written tests, or by final exam
The final grade is calculated based on the laboratory practical classification (30%), research project and its oral presentation (20%) and the classification of the write component (50%).
The laboratory practical component is continuously evaluated based on attendance, planning of experimental work and interpretation and discussion of the results obtained. Additionally, students should present a research project based on the main biochemical markers for diagnosis or monitoring a selected pathology. The theoretical component can be assessed by continuous assessment, with 2 written tests, or by final exam
The final grade is calculated based on the laboratory practical classification (30%), research project and its oral presentation (20%) and the classification of the write component (50%).
Certificações
