2024
Environmental Pharmacology
Name: Environmental Pharmacology
Code: CMS13765I
3 ECTS
Duration: 15 weeks/78 hours
Scientific Area:
Ciências Farmacêuticas
Teaching languages: Portuguese
Languages of tutoring support: Portuguese
Presentation
The UC aims to provide students with knowledge about the presence in the environment of drugs and other substances harmful to human health, to identify the routes of environmental exposure, the definition of Ecopharmacovigilance and the approaches of environmental regulation and Risk Assessment.
Sustainable Development Goals
Learning Goals
At the end of the course the student should be able to:
Present an historical perspective on Environmental Pharmacology
Understand the dimension and extension of pharmaceuticals presence in the environment.
Identify Pharmaceutical active compounds (PhACs) and Personal Care Products (PPCPs) detected in the environment and describe their effects.
Identify pharmaceuticals environmental exposure pathways.
Understand the boomerang effect and the importance of gene-environment interaction in the process.
Describe the use of Sewage Epidemiology regarding illicit drugs and pharmaceuticals.
Characterize the connection between pharmaceuticals, emerging disease vectors and climate change.
Define EcoPharmacovigilange and its connection with safe pharmaceutical disposal and the establishment environment standards by national and international regulators.
Describe the Environmental Risk Assessment of PhACs and PPCPs.
Ability to summarize the course by means of "Student Elevator Talks".
Present an historical perspective on Environmental Pharmacology
Understand the dimension and extension of pharmaceuticals presence in the environment.
Identify Pharmaceutical active compounds (PhACs) and Personal Care Products (PPCPs) detected in the environment and describe their effects.
Identify pharmaceuticals environmental exposure pathways.
Understand the boomerang effect and the importance of gene-environment interaction in the process.
Describe the use of Sewage Epidemiology regarding illicit drugs and pharmaceuticals.
Characterize the connection between pharmaceuticals, emerging disease vectors and climate change.
Define EcoPharmacovigilange and its connection with safe pharmaceutical disposal and the establishment environment standards by national and international regulators.
Describe the Environmental Risk Assessment of PhACs and PPCPs.
Ability to summarize the course by means of "Student Elevator Talks".
Contents
Historical perspective
Pharmaceuticals in the Environment.
Pharmaceutical active compounds (PhACs) and Personal Care Products (PPCPs) as contaminants: Human and Veterinary Drugs, Diagnostic agents, Consumer Chemicals, Fragrances, Sunscreens, excipients, Nutraceuticals, Metals. Environmental effects
Agrochemicals, its residues and metabolites, circulation and unwanted effects.
Environmental exposure to Pharmaceuticals.
Environmental Signaling and Epigenetics: Theoretical Basis of Environmental Pharmacology.
The Boomerang Effect.
The Sewage Epidemiology approach for illicit drugs and pharmaceuticals
Pharmaceuticals, emerging Disease Vectors and Climate Change.
EcoPharmacovigilange.
Pharmaceutical disposal and environment standards: European Union; United States Environmental Protection Agency; World Health Organization.
Environmental Risk Assessment (ERA) of PhACs and PPCPs.
Methods for the control of pharmaceuticals in the environment.
Case Studies.
Summary -"Student Elevator Talks.
Pharmaceuticals in the Environment.
Pharmaceutical active compounds (PhACs) and Personal Care Products (PPCPs) as contaminants: Human and Veterinary Drugs, Diagnostic agents, Consumer Chemicals, Fragrances, Sunscreens, excipients, Nutraceuticals, Metals. Environmental effects
Agrochemicals, its residues and metabolites, circulation and unwanted effects.
Environmental exposure to Pharmaceuticals.
Environmental Signaling and Epigenetics: Theoretical Basis of Environmental Pharmacology.
The Boomerang Effect.
The Sewage Epidemiology approach for illicit drugs and pharmaceuticals
Pharmaceuticals, emerging Disease Vectors and Climate Change.
EcoPharmacovigilange.
Pharmaceutical disposal and environment standards: European Union; United States Environmental Protection Agency; World Health Organization.
Environmental Risk Assessment (ERA) of PhACs and PPCPs.
Methods for the control of pharmaceuticals in the environment.
Case Studies.
Summary -"Student Elevator Talks.
Teaching Methods
Lectures will be centered in oral exposure supported by audio-visual media, with constant stimulation of students participation, appealing to and elaborating atop of pre-existing knowledge acquired along the academic progression, and complemented with the exploration of relatable case studies that will allow students to easily frame the issues with their personal experience.
Theoretical-practical classes will put in evidence, by the presentation and discussion of state-of-the-art papers by the students, the presence, toxicity and bioaccumulation of pharmaceuticals in the biota and humans, putting forward contemporaneous evidence of the deleterious effects towards ecosystems and human health.
Evaluation:
Theoretical (75%) two tests OR a final exam.
"Student Elevator Talks" (5%).
Poster presentation (20%).
Theoretical-practical classes will put in evidence, by the presentation and discussion of state-of-the-art papers by the students, the presence, toxicity and bioaccumulation of pharmaceuticals in the biota and humans, putting forward contemporaneous evidence of the deleterious effects towards ecosystems and human health.
Evaluation:
Theoretical (75%) two tests OR a final exam.
"Student Elevator Talks" (5%).
Poster presentation (20%).
Certificações
